SEPIA [se]
Lindsley & Grell, 1972, pp. 224-225
location: 3-26.0.
discoverer: E.M. Wallace, 13e10.
references: Bridges and Morgan, 1923, Carnegie Inst. Wash. Publ. No. 327: 86 (fig.).
Sturtevant and Beadle, 1939, An Introduction to Genetics, Saunders, p. 64 (fig.).
phenotype: Eye color brown at eclosion, darkening to sepia and becoming black with age. Pigmentation of ocelli normal. Chromatographically, se eyes characterized by having no red pigment and an accumulation of the yellow pigment, sepiapterin (Hadorn and Mitchell, 1951, Proc. Natl. Acad. Sci. U.S. 37: 650-65); other pteridines present in greater-than-normal amounts. se/+ can be distinguished from +/+ in that it has more isoxanthopterin and other pale pteridines; the red drosopterins are at wild-type level, so that se appears completely recessive on ordinary visual examination (Ziegler-GŁnder and Hadorn, 1958, Z. Vererbungslehre 89: 235-45). Structure of the sepiapterin is 2-amino-4-oxo-6-lactyl-3,4,7,8-tetrahydropteridine (Forrest and Nawa, 1962, Nature 196: 372-73). Eye color autonomous in se eye disks transplanted into wild-type hosts (Beadle end Ephrussi, 1936, Genetics 21: 230). RK1.
color figure: P. A. Otto (original)
photograph: P. A. Otto (original)