Lindsley & Grell, 1972, pp. 209-210
location: 3-52.0 [0.3 units to the right of kar (Schalet)].
discoverer: Bridges, 38c4.
references: Glassman and Mitchell, 1959, Genetics 44: 153-62. Hubby and Forrest, 1960, Genetics 45: 211-24. Chovnick, Schalet, Kernaghan, and Talsma, 1962, Am. Naturalist 96: 281-96. Chovnick, Schalet, Kernaghan, and Krauss, 1964, Genetics 50: 1245-59.
phenotype: Eye color reddish brown; contains about 35 percent normal red pigment and 82 percent normal brown pigment (Nolte, 1955, J. Genet. 53: 1-10). Lacks detectable amount of xanthine dehydrogenase, like ma1 (Forrest, Glassman, and Mitchell, 1956, Science 124: 725-26; Glassman and Mitchell, 1959; Hubby and Forrest, 1960). Accumulates enzyme's substrates, hypoxanthine and 2-amino-4-hydroxypteridine and lacks its products, uric acid and isoxanthopterin (Mitchell, Glassman, and Hadorn, 1959, Science 129: 268-69). In vitro and in vivo complementation between ma1+ and ry+ demonstrated (Glassman, 1952, Proc. Natl. Acad. Sci. U.S. 48: 1491-97; Glassman and McLean, 1962, Proc. Natl. Acad. Sci. U.S. 48: 1712-18). Pigmentation nonautonomous in ry eye disks transplanted to wild-type hosts (Hadorn and Schwink, 1956, Nature 177: 940-41). RK1.
cytology: Placed in region 87D-F, on basis of its inclusion in Df(3R)ry = Df(3R)87D-E;87E-F (Grell, 1962, Z. Vererbungslehre 93: 371-77).
other information: separable into at least six non-complementing but recombinationally separable sites (Chovnick, Sehalet, Kernaghan, and Krauss, 1964). ry recombines with ry26 and ry2 but not with ry23, ry9, ry8, or ry42 and has been interpreted as an intracistronic rearrangement.
color figure: P. A. Otto (original)
photograph: P. A. Otto (original)